Wednesday, January 3, 2018

Glucagon Receptor Structure Offers New Opportunities for Type 2 Diabetes Drug Discovery

The crystal structures of the full-length human glucagon receptor (GCGR): orange (extracellular domain), blue (transmembrane domain), green (stalk), magenta (the first extracellular loop), red (NNC1702), yellow (NNC0640) and cyan (mAb1). (Image by Dr. WU Beili) (PRNewsfoto/Shanghai Institute of Materia M)- Complex structure of a class B GPCR bound to an analogue of its endogenous ligand ignites new excitement in GPCR research SHANGHAI, Jan. 4, 2018 /PRNewswire/ -- Class B G protein-coupled receptors (GPCRs) exert essential action in hormonal homeostasis and are important therapeutic...




from PR Newswire: //www.prnewswire.co.uk/news-releases/glucagon-receptor-structure-offers-new-opportunities-for-type-2-diabetes-drug-discovery-667961683.html
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